NATIONAL TAIWAN UNIVERSITY
國立臺灣大學
REASERCH TEAM
林澤教授
基於 N-gram 分子圖以及新穎圖神經網路架構之快速藥物篩選平台
Rapid drug screening using N-gram molecular graphs via a novel architecture of graph neural network
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Drug-target affinity (DTA) prediction is crucial for drug discovery.
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We proposed N-gram graph DTA (NG-DTA) [1] based on graph neural networks (GNN) with self-attention to utilize drug and N-gram protein molecular graphs.
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NG-DTA achieves the best performance among deep-learning based DTA models.
邱浩傑教授
速效生物膜清除組合
Fast-Acting Biofilm Removal Combination
Biofilm-associated infections, such as catheter-associated urinary tract infections (CAUTIs), impose a substantial burden on healthcare systems, so the development of effective therapies is crucial. According to Future Market Insights, the global market for treating CAUTIs was valued at USD$83.2 billion in 2022 and is projected to reach USD$171.56 billion by 2033, with a steady CAGR of 6.8%. This presents a notable business opportunity for the development of innovative solutions aimed at preventing or treating CAUTIs.
廖偉智醫師、王偉仲教授、臺大MeDA Lab & 臺大醫院廖偉智醫師團隊
助胰見-創新人工智慧胰臟癌輔助偵測系統PANCREASaver -Innovative Artificial Intelligence-assisted Detection Tool for Pancreatic Cancer-
CT is the major modality for detecting pancreatic cancer(PC), but early PCs are often obscure or even invisible tothe naked eye on CT, with approximately 40% of PCs smaller than 2 cm being missed on CT. Leveraging the latest advances in artificial intelligence, PANCREASaver is an in-novative end-to-end fully automatic computer-aided detection tool for PC.
駱遠教授
可攜式各向同性定量差分相位對比顯微鏡系統Multifunctional Portable Quantitative Differential Phase Contrast Microscope
本技術透過光瞳工程，在影像的傅立葉平面放置數位光瞳，以提供樣本結構光照明。經推算系統的相位轉移方程式後，即可透過相機所擷取之光強度資訊回推樣本相位，實現相位回復。此定量相位資訊可以二維或三維相位圖呈現，而獲取的相位因可以轉換成樣本高度，得利用於各種病理與細胞研究。
透過將硬體更換為FPGA，其平行運算能力得以提升系統運算速度，再藉由自動化設計，使得光瞳顯示得以與相機擷取功能同步，縮短影像擷取時間以降低細胞環境隨時間造成的重建誤差，進一步提升系統準確度。
蘇東弘副教授、陳世淯博士、王安邦特聘教授
Fast and Microliter Immunostaining Platform for Biomedical Applications
Thin-film Direct Coating method
Immunostaining
Immunoassay is the most common technique for biochemical analysis or clinic diagnosis by using the high specificity of antibody for target antigen. It includes
1. Western blotting
2. Immunochromatographic tests (e.g. rapid Ag test)
3. Immunohistochemical staining
4. Immunofluorescence staining
陳明汝特聘教授
開發提升乳牛健康之新穎次世代益生菌組合
Development of novel next-generation probiotics for health promotion in dairy cattle
A one-year field trial in dairy farm is now on going. We will evaluate the effects on dairy cows’ health, milk performance, and reproduction. The calves they give birth will be also evaluated the health and growth performance. This will be the first novel next-generation probiotic product applying for dairy cow and calf for health promotion and improvement of growth/production performance.
臺大生物資源暨農學院實驗林管理處
臺大實驗林香杉精油與林下經濟產品開發成果
臺大實驗林-香杉精油(Cunninghamia konishii)取自臺大實驗林之人工林疏伐木，並由轄下木材利用實習工廠進行煉製，以蒸餾法對粉碎的香杉樹木材部進行萃取。經GC-MS分析鑑定本香杉精油成分以倍半萜類含氧化合物雪松醇-Cedrol (53.03%)為主，以單萜類含氧化合物(α-Terpineol)、(α-Pinene)及倍半萜類化合物-香柏醇(α-Cedrene)次之。香杉精油抗蟎活性之研究時表示Cedrol 對於抑制木材腐朽菌有不錯的效果，α-Cedrene對熱帶無爪塵蟎具有良好的抗蟎活性，Thujopsene成分，它具有良好的防腐劑、鎮靜、殺蟲及抗真菌活性，此成分除了可做為開發植物性藥劑（Botanical drugs）的潛能之外，亦可提供人們健康的生活環境。
NTU SPARK Office
國立臺灣大學SPARK專案辦公室
National Taiwan University (NTU) SPARK office, with internal abundant business unions, research capacity, and the best medical system - NTU Hospital, offer sub-project members the commercialize training courses and outsourcing connections to help out research in transforming product development , marketing and business planning and other important cross-field talents training, in order to achieve the effect of transforming R&D results into contributions to the industry.
國立臺灣大學精準醫學推動中心
「精準醫學推動中心」人才培育計畫整合臺大醫學院、藥學專業學院、電機資訊學院、工學院、管理學院等臺大一級學術單位，與臺大健康資料研究中心(Health Data Research Center)、醫學院附設醫院、附設癌醫中心醫院和附設醫院智慧醫療中心（臨床場域、資料與諮詢），加上臺大人工智慧技術與全幅健康照護聯合研究中心、基因體暨精準醫學研究中心、智慧健康科技研發中心、人工智慧與機器人研究中心、臺大生物技術研究中心等跨域專業及實務鏈結，開設符合「醫藥生技產業的大趨勢」與「新興精準健康產業需求」之高階前瞻彈性課程、相關見實習課程和配套活動。不但達到學用合一，亦能促進產業技術提升與國際化，目標族群為全臺對精準健康與醫療產業有興趣的在校生和園區、法人、業界學員及投資者等。
國立臺灣大學研發處產學合作總中心創新育成中心
Center of Industry-Academia Collaboration
地址：臺北市大安區羅斯福路四段一號禮賢樓六樓
Tel：(02)3366-9945
Email：ordiac@ntu.edu.tw