碳點應用於非法藥物檢測工具開發

Carbon dots applied to illicit drug detection tool

​張煥宗教授

Email:changht@mail.cgu.edu.tw

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Among the many nanomaterials, carbon-based materials are very suitable for the development of detection probes due to their low biotoxicity. In particular, the unique fluorescence and electronic properties of carbon quantum dots with three-dimensional dimensions smaller than 10 nm make them very suitable for drug sensing applications. In addition, the synthesis process of carbon quantum dots is very simple and inexpensive, and most organic molecules can form carbon quantum dots after high temperature heating, which makes the composition of carbon quantum dots very diverse. The growing number of illegal drugs is causing many social problems. Although traditional detection techniques are sensitive and accurate, there is still a lack of effective field detection tools. This technique uses L-arginine and D-phenylalanine as carbon sources to synthesize two different carbon dot probes. Combined with chromatographic test paper and liquid quenching techniques, we develop test paper and liquid carbon point drug detection platforms respectively. These platforms will be used for rapid screening of drugs (4-chloroethyl cathinone) and sleeping pills (Nimetazolam) to demonstrate the potential of carbon dots in field illicit drug detection. This technique has experimentally validated the feasibility and potential of carbon point probes for on-site illicit drug detection. In future technology development, the performance of these carbon point probes can be further optimized to improve detection effectiveness and accuracy. In addition, to achieve wider application, this technology can be explored for the detection of other illicit drugs and hazardous substances. This will help provide public health and law enforcement agencies with more reliable on-site detection tools to help combat illegal drug abuse and trafficking.